OsseoConduct™ β-TCP Granules


3rd Generation Beta Tri Calcium Phosphate

 Completely resorbed in 4-6 months and replaced by healthy vital bone.

Click here to view bTCP Study


3rd Generation Beta Tricalcium Phosphate Bone Graft

OsseoConduct™ is a  Trade Mark of Steiner Biotechnology.  This 3rd generation bTCP combines the features of biocompatibility, resorabability and osteoconductivity to produce the latest technology in bone grafting materials.  OsseoConduct™ is a state of the art micro-porous beta tricalcium phosphate that provides what you are looking for in a granular bone graft material. Unlike its predecessors, this 3rd generation BTCP resorbs completely in 4- 6 months and is replaced by bone.  It also contains micro-pores unlike the macro-pores that previous BTCP products contained. Recent studies concluded that macro-pores allowed for bacteria to become entrapped causing bacterial colonization resulting in graft failure.   As a matrix for cell adhesion and proliferation in combination with cell mediated resorption, grafting with OsseoConduct™ produces normal bone in a short time period (figure 1). OsseoConduct™ granules avoid all of the things you don’t want in a graft material such as inflammatory reactions resulting from residual proteins, potential disease transmission and the inability to be resorbed preventing bone formation.

OsseoConduct™ is a bone graft matrix for the natural process of bone remodeling that converts this biocompatible synthetic graft material into normal bone. During resorption OsseoConduct™ granules provide the calcium and phosphate for mineralization of living bone without an inflammatory response. Any graft material that includes proteins will have a varying degree of inflammatory response. Other graft materials without proteins are considered non-pyrogenic because they produce a small inflammatory response. OsseoConduct™ is one of the rare graft materials that is pyrogen free because there is no detectable inflammatory response.  When grafting with OsseoConduct™ granules it is the process of remodeling rather than encapsulation that produces normal bone in a short amount of time. OsseoConduct™ granules are resorbed in 6 months.

OsseoConduct™ granules undergo a rapid rate of resorption due to its unique physical properties. Other resorbable granular bone grafts require osteoclasts for resorption to take place. Osteoclasts exist only in mineralized bone. In order for other bone graft materials to be resorbed they must be encased in mineralized bone first before absorption can occur. Therefore, the resorption process will take many months or years. OsseoConduct™ granules are able to be resorbed by monocytes (phagocytes) which are found in soft connective tissue (figure 2, 3). OsseoConduct™ granules begin the resorbtive process soon after grafting and this process continues providing space for ingrowth of mineralized bone. The result is a more rapid and complete replacement of OsseoConduct™ granules with normal bone while maintaining shape and volume. Unlike allografts and xenografts OsseoConduct™ produces bone with normal physiology and architecture.

As with all of Steiner Biotechnology products OsseoConduct™ has been through years of development and clinical testing. As a clinician driven company OsseoConduct™ was developed to meet the following criteria:

  1. The graft material must not elicit an inflammatory response.
  2. The graft material must have no potential for disease transmission.
  3. The material must maintain volume as it is being resorbed and new bone is formed.
  4. The graft material must produce bone with normal form and function.
  5. The material must be significantly resorbed in 3 months.
  6. The material must be able to handle reasonable load in order to resist deformation during the remodeling phase.
  7. The material must be cost effective for the patient and practitioner.
  8. The graft material must be easy to apply.
  9. The graft material must be designed to prevent bacterial colonization.

In the oral cavity it is difficult to perform sterile surgical procedures.  For this reason the graft material should be designed to prevent bacterial colonization. Any graft material with macro pores such as allografts and xenografts can be colonized by bacteria that the body has no defense against. Therefor,  OsseoConduct™ granules were designed with micropores to prevent bacterial colonization.

Steiner Biotechnology is proud to introduce OsseoConduct™ granules for your bone grafting needs. For ease of application and to maintain the ideal environment for bone growth, it is advised that OsseoConduct™ granules be used with the wetting agent Hydrase™. Hydrase™ provides the ideal pH, purity and ion concentration for osteoblast vitality and makes application of the granules simple. OsseoConduct™ granules can also be combined with Socket Graft Putty™ for missing walls after extraction, Ridge Graft™ for ridge and sinus augmentation surgery and for perio lesions. OsseoConduct™ granules are provided in sterile packets that can be placed in the sterile surgical field.

OsseoConduct™ granules are available in two sizes:
OsseoConduct™ Perio Granules 250- 500 microns (.25 mm-.5mm) for periodontal lesions
OsseoConduct™ Standard Granules 500-1000 microns (.5mm-1mm) for socket grafting, ridge augmentation and sinus augmentation

Both sizes Available in quantities of .5cc and 1cc.

OsseoConduct™ Figure 1 – OsseoConduct™ granules.

OsseoConduct™ Figure 2 – Human histology 40 days. Monocytes lining and resorbing an OsseoConduct™ granule.

OsseoConduct™ Figure 3 – Human histology 40 days. Monocytes resorbing into an OsseoConduct™ granule.

OsseoConduct™ Figure 4 – 4 months in ridge augmentation. As the graft material becomes bone the monocytes shown in the previous histology fuse and become osteoclasts as shown in this histology section.

OsseoConduct™ Figure 5 – 4 months ridge augmentation.  Showing osteoconduction

OsseoConduct™ Figure 6 – 4 months after ridge augmentation with OsseoConduct™ granules mixed with Ridge Graft™

OsseoConduct™ Figure 7 – Pre op photograph

OsseoConduct™ Figure 8 – 3 month post op photo prior to implant placement

OsseoConduct™ Figure 9 – Ridge regenerated with OsseoConduct™ granules mixed with Ridge Graft™ 3 months post augmentation.

OsseoConduct™ Figure 10 – 3 month post ridge augmentation histology