OsseoConduct™ Histology

OsseoConduct™ βTCP granules undergo a rapid rate of resorption due to its unique physical properties, providing space for ingrowth of mineralized bone. Other resorbable granular bone grafts require osteoclasts for resorption to take place. Osteoclasts exist only in mineralized bone. In order for other bone graft materials to be resorbed, they must be encased in mineralized bone first before absorption can occur. Therefore, the resorption process will take many months or years. OsseoConduct™ granules are able to be resorbed by monocytes (phagocytes) which are found in soft connective tissue.
Histology of core sample, 40 days
Monocytes lining and resorbing an OsseoConduct™ βTCP granule
Histology, 40 days
Monocytes resorbing into an OsseoConduct™ βTCP granule
4 months in ridge augmentation
As the graft material becomes bone, the monocytes shown in the previous histology fuse and become osteoclasts as shown in this histology section.
4 months ridge augmentation showing osteoconduction
4 months after ridge augmentation with Ridge Graft Kit™
Pre op photograph
3-month post op photo prior to implant placement
3 months post augmentation, ridge regenerated with Ridge Graft Kit™

MEMBER:

American Society for Bone and Mineral Research (ASBMR)

Tissue Engineering and Regenerative Medicine International Society (TERMIS)