As osteoblasts migrate through the graft, they reach an implant surface and produce implant integration. In this manner implants can be placed at the same time as grafting with the confidence that complete implant integration will occur.
The tissue engineering of bone requires the biologic stimulation of host cells. Due to the short half life of growth factors when placed in the graft site and the inability of a single growth factor to orchestrate the complex temporal and spatial molecular reactions needed to produce tissue, the use of single growth factors for the biologic stimulation of host cells produces only limited bone growth.
For these reasons, Sinus Graft™ does not use growth factors, but instead contains SL Factor, which stimulates the cell to increase the production of growth factors and other signaling molecules.